Association between Functional Status of Patients and Cognitive Impairment in End Stage Renal Disease

Abstract

ABSTRACT

Objective: The increased incidence of diabetes, hypertension in third world countries has lead to an increase in end stage renal disease which in turn escalates the burden of dialysis on patients and caregivers. Dialysis is associated with many serious physical and mental disturbances. The aim of this study is to highlight the importance of screening for cognitive impairment and depression in End stage renal disease because cognitive impairment can impair the activities of daily living and overall quality of life.  

Methods: 150 patients were included in a study after fulfilling the inclusion and exclusion criteria. They were screened for cognitive impairment by using the Montreal cognitive assessment scale, for depression by using Hospital Anxiety and Depression scale and Barthels index for assessment of activities of daily living. 

Results: Of 150 patients most were males (56%) and females were (44%) out of which 36.67% males and 32.67% of females were cognitively impaired. Most patients were hypertensive and unemployed.  There was no significant social demographic association observed for cognitive impairment. The patients with cognitive impairment need assistance in feeding, bathing and mobility as compared to patients with no cognitive impairment.  

Conclusion: Our study revealed that cognitive impairment is present in patients and it is related with activities of daily living. The presence of depressive symptoms and anxiety is also affecting activities of daily living difficulty in ambulatory hemodialysis patients. Patients especially need help in climbing stairs and minor help in transferring, occasional bladder help, minor help in feeding and minor help during walk. 

Key words: Cognitive impairment, End stage renal disease, Dialysis, Activities of daily living.