SYED LAYEEQ AHMAD, ABU NOEM FAROOQUI, FARAH ASAD, MAHMOOD,
AFTAB MERCHANT.

ABSTRACT

Background: Neisseria Meningitis & streptococcus pneumoni being the most common organisms in bacterial meningitis, penicillin resistance is emerging fast in them worldwide. As there are very few studies in this regard a study was done at Abbasi Shaheed Hospital to determine the comparative yield of causative organisms along with observing penicillin resistance in these organisms causing pyogenic meningitis.

Materials And Methods: One hundred and twenty patients were enrolled out of which 50 were selected for this study. Among these 38 were males & 12 were females. Lumber puncture was done on all of them and C.S.F was sent for Gram staining and culture.

Result: Neisseria meningitidis and Streptococcus Pneumoniae were responsible for 48% and 40% of cases respectively. Haemophilus influenzae showed a very low occurrence rate. of 8%. While 16.25% of isolated pneumococcus were resistant to penicillin.

Conclusion: Majority of cases occurred in young adults and in winter season. Neisseria meningitidis and Streptococcus Pneumoniae are the most frequent causative organisms. The Penicillin resistance is significantly high (P<.000) among pneumococcal strains.

For Full text contact to:
Prof. Dr. Farah Mansuri
editor@annals-ashkmdc.org

Assistant Professor, Department of Medicine, Karachi Medical & Dental College, Karachi *
Department of Internal Medicine,Abbasi Shaheed Hospital,Karachi. *
Assistant Professor, Department of Community Health Science, Karachi Medical and Dental College, Karachi *
Department of Internal Medicine,Abbasi Shaheed Hospital,Karachi. *