SHAHNAZ HASAN SIDDIQUI, AZRA SULTANA, FARAH ASAD.

ABSTRACT

Objective: The Objective of this study was to determine the maternal and perinatal outcome in HELLP syndrome and to reflect the importance of early diagnosis of HELLP syndrome in eclampsia and preclampsia.

Methods: A case control study was designed; where retrospective review of 15 cases of confirmed HELLP syndrome from January 1997 to January 2002 was undertaken at Gynae /Obstetrics Unit II, Abbasi Shaheed Hospital and thirteen controls were selected of eclampsia with no evidence of HELLP. Maternal and neonatal complications were recorded and resolution of laboratory indices was measured.

Results: Seventy five percent of the women were delivered within 24 hours of diagnosis; out of this, 83.73% were delivered by caesarean section. There were 73.3% pre-term deliveries and 75% of the babies were admitted to the neonatal intensive care unit (NICU). The peri-natal mortality was 46.66 % while the maternal mortality was 20%. The mean interval of resolution of laboratory indices to within normal ranges was twelve (7-35) days. The neonatal morbidity was high and was closely related to the period of gestation at delivery.

For Full text contact to:
Prof. Dr. Farah Mansuri
editor@annals-ashkmdc.org

Department of Obstetrics and Gynaecology, Abbasi Shaheed Hospital, Karachi *
Karachi Medical & Dental College ASH (Deptt. of Pathology Gynae & Urology ). *
Assistant Professor, Department of Community Health Science, Karachi Medical and Dental College, Karachi *