SHAHNAZ HASAN, BUSHRA HASHIM, AZRA SULTANA.

ABSTRACT

Objective: To evaluate the effects of intravenous iron-sucrose versus oral iron hydroxide polymaltose complex in Iron deficiency anemia after 28 weeks of pregnancy to 36 weeks of Pregnancy.

Study Design: A random, prospective, open study with individual benefit was performed involving 50 patients with haemoglobin levels between 8 and 10 g/dl and a ferritin value of less than 50 mg/l. In the intravenous group, the iron dose was calculated from the following formula: weight before pregnancy (Kg) x (120 g/l - Actual haemoglobin [g/l]) x 0.24 + 500mg. The oral group received 200 mg of iron hydrooxide poly-maltose complex per day for four weeks. Treatment efficacy was assessed by measurement of haemoglobin and ferritin level on 1st day of visit , then four weeks after therapy and at delivery. Results were expressed as mean. Student t-test was applied for the result with p < 0.05 considered significant.

Result: An increase in hemoglobin 1gm/dl after 4 weeks in intravenous therapy group and 1gm/dl after 4 weeks of therapy in PO group. The serum ferritin level is slightly more raised in intravenous group than in oral group.

Conclusion: Iron sucrose as intravenous therapy has better results for increasing hemoglobin % level as well as serum ferritin level, in-group of 28 weeks to 36 weeks pregnant female group.

For Full text contact to:
Prof. Dr. Farah Mansuri
editor@annals-ashkmdc.org

Assistant Professor, Department of Orthopaedics, Abbasi Shaheed Hospital & Karachi Medical & Dental College *
Post Graduate Trainee Registrar, Department of Orthopaedics, Abbasi Shaheed Hospital & Karachi Medical & Dental College *
Post Graduate Trainee Registrar, Department of Orthopaedics, Abbasi Shaheed Hospital & Karachi Medical & Dental College *