*NISAR SHAIKH, **UZMA FASIH, ***M.S FEHMI, ****ARSHAD SHAIKH

ABSTRACT

Objective:The objective of our study was to prevent the recurrence of pterygium with application of intraoperative Mitomycin C following pterygium excision using bare sclera technique.

Materials & Methods: This was an observational study and carried out at eye department Abbasi Shaheed Hospital Karachi. Fifty patients were studied over a period of 9 months. Patient information regarding visual aquity ,intraocular pressure ,retinoscopy ,condition of cornea ,conjunctiva and retina were recorded on a predesigned performa. Patients were admitted in the ward and operated in sterilized operation theatre environment .Mitomycin C was applied on bare sclera in a concentration of 0.02%(0.2 mg/ml) for 2.5 minutes and irrigated with copious amount of normal saline afterwards. Patients were discharged next day on mild steroid like flouromethalone and an antibiotic ointment. Follow-up was done on first week ,one month, 3 months and six months. Rate of recurrences and postoperative complications were noted down.

Results: There were 72% male and 28% female patients .Most common presenting age group was between 30-40 years of age(42%). Primary pterygia included in the study were 90%(45 patients) and recurrent were 10%(5 patients). Recurrence rate in primary pterygia was 6.6%(3 patients ) and in recurrent pterygia 20%(1 patient). No major complication was recorded.

Conclusion: It was concluded that intraoperative application of Mitomycin C on bare sclera is safe and effective in preventing the recurrence of pterygium after excision provided potential complications of Mitomycin C are sufficiently addressed.

Key Words: Pterygium, Bare Sclera, Mitomycin C.

Abbreviations: MMC:(Mitomycin C), UV Rays:(ultraviolet rays), DNA (deoxyribinuclic acid).

For Full text contact to:
Prof. Dr. Farah Mansuri
editor@annals-ashkmdc.org

*Assistant Professor
**Assistant Professor
***Associate Professor
****Professor & Head of Eye Department Eye Dept., Karachi Medical & Dental College Abbasi Shaheed Hospital Karachi.