1MUGHIS UDDIN AHMED, 2MOTASIM AHMED AND 3NEARCHOS YIANNAKOU

ABSTRACT

Objective: Abstract Objective: Infection with MSSA and MRSA is quite common in the region as well as around the globe which results in a substantial number of morbidities and mortalities in a population. This study is designed to find out frequencies of MSSA and MRSA in the Pediatric and adult populations in the Eastern Region. We also assess prevalence of Community Associated (CA) MRSA and Hospital Associated (HA) MRSA along with antibiotic sensitivity pattern.

Materials and Methods: It is a case series study. It was done at the King Abdulaziz Hospital (National Guard Health Affairs) Al-Ahsa, Kingdom of Saudi Arabia. A total of 1930 comprising of MRSA 463 and MSSA 1467 which were confirmed by CLSI (Clinical Laboratory Standard Institute) 2008. All standards of JCIA (Joint Commission for International Accreditation) and CAP (College of American Pathologist) were followed, as our laboratory is accredited by both, in MRSA identification of CA-MRSA (Community associated) and HA-MRSA (Hospital associated) were also done. Antibiotics sensitivity pattern is also recorded.

Results: Overall MRSA isolates were 24.0% whereas MSSA were 76.0%. MRSA varies from 22-26% from 2006 to 2008 and MSSA varies from 74-76% from 2006 to 2008. The overall male and female were 52.0% and 48.0% respectively with a ratio of 1.1:1.0. The total CA MRSA were 72.0% and HA MRSA were 28.0%. Both MRSA and MSSA were 18.55% Pediatrics and 81.45% were adults. MRSA is 100% sensitive to vancomycin, 98.0% to rifampin whereas MSSA is 100% sensitive to ciprofloxacin, cloxacillin, vancomycin and 99.0% to trimethoprim with sulfamethoxazole.

Conclusion: It is evident from this study that both MRSA and MSSA are quite common in Eastern Region of Saudi Arabia. We should use antibiotics properly to avoid emergence of resistance and also implement infection control practices to overcome spread of these infections in the population.

Key Words: MRSA, MSSA, Community Associated, Hospital Associated .

For Full text contact to:
Prof. Dr. Farah Mansuri
editor@annals-ashkmdc.org

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