1 KHURRAM DANIAL, 2YASMEEN MUMTAZ, 1SHOAIB ARIF, 1KAMRAN SHAHID, 1WAQAR H. KAZMI

ABSTRACT

Objective: To determine factors associated with increased time to wait-listing, and to determine the factors associated with probability of being wait-listed for cadaveric kidney transplant.
Material & Methods: This study is a secondary analysis of a prospective cohort study, the Dialysis Morbidity and Mortality Study (DMMS) Wave II. The DMMS Wave II is a prospective study of about 4500 incident dialysis patients from about 790 dialysis units in U.S. Patient population included all potential transplant candidates in DMMS Wave II who initiated dialysis in 1996-97, who completed a patient questionnaire, were ³18 years of age, and had at least a 2 year follow-up since the initiation of dialysis (cohort 1). For Cohort 2 all adult (³ 18 years of age) 1996-97 incident dialysis patients in DMMS Wave II who completed a patient questionnaire, and were wait-listed for a cadaveric kidney transplant were included. Pre-emptive transplant recipients, patients returning to dialysis and those who had a prior kidney transplant were excluded.
Results: Of the 2414 patients in first cohort, 508 patients got accepted for kidney transplant and were placed on the wait-list. A stepwise selection process was then used for developing the multivariate Cox Proportional Hazards Regression Model, where all independent variables with univariate associations of p.£10 were allowed to enter the model
Key words: Late referral, Nephrology.

For Full text contact to:
Prof. Dr. Farah Mansuri
editor@annals-ashkmdc.org

1Department of Nephrology, KMDC & Abbasi Shaheed Hospital Karachi
2Department Of Community Medicine Dow University of Health Sciences