SENSITIVE, RESISTANT AND MULTIDRUG RESISTANT PSEUDOMONAS AERUGINOSA AT OUR HEALTH CARE SETTING IN EASTERN REGION OF SAUDI ARABIA
1MUGHIS UDDIN AHMED, 2FATIMA SAYED, 3NADIA AL HAWASHIM, 4MOTASIM AHMED,
5NEARCHOS YIANNAKOU, 6RESHMA FAROOQ, 7ALI RIFAT SAYED
ABSTRACT
Objective: This
study is designed to observe sensitive (S), resistant (R), multi-drug
resistant (MDR) Pseudomonas aeruginosa along with other isolates
in our population at Eastern Region of Saudi Arabia.
Materials and Methods: This study is a retrospective
observational study which was designed to collect data of different
stains of Pseudomonas aeruginosa, whether Sensitive (S), Resistant
(R), Multi-Drug Resistant (MDR) along with other gram negative organisms
isolated from different sites from 1st January 2004 to 31st December
2011 at King Abdulaziz Hospital (NGHA) Al-Ahsa, Eastern Region of
Kingdom of Saudi Arabia (KSA). All Necessary techniques were used
to do culture and sensitivity of these organisms. Acinetobacter
baumannii is excluded from other gram-negative organisms isolated
from different sites.
Results: The total number of isolates was 6603
out of which 2977 (45%) were Pseudomonas aeruginosai and the other
gram negative isolates were 3626 (55%). Conclusion: Inappropriate
use of antibiotics resulted in the increase in resistant and multi-drug
resistant strains of not only Pseudomonas aeruginosa but other gram-negative
organisms. Antibiotics policies & procedures, infection control
& prevention should be followed. We should also start antibiotic
stewardship program at all hospitals and other healthcare settings.
Key Words: Pseudomonas aeruginosa, Resistant (R),
Multi-Drug Resistant (MDR), ESBL (Extended Spectrum Beta Lactamase),
PBP (Penicillin Binding Proteins)
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