RISK FACTORS FOR SURGICAL SITE INFECTION IN CLEAN SURGERIES IN ABBASI SHAHEED HOSPITAL
OMEMA SALEEM, M. JAMALUDDIN, RIZWAN A. KHAN, S.M. ABBAS HUSSAIN
ABSTRACT
Objective: To assess
the risk of surgical site infection in clean surgeries associated
with age, sex and duration of surgery in Abbasi Shaheed Hospital.
Subjects and methods: This study is a Case control
study and was conducted in surgical Unit-1, Abbasi Shaheed Hospital,
Karachi from January 2006 to December 2008. Its sample size is Non-probability,
convenience and 150 patients were taken for this study in which
100 patients with healthy surgical site were taken as control while
50 patients with infected surgical site were taken as the cases.
All male and female patients of age between 18 to 55 years were
included in this study. For all diabetic and non-diabetic patients
who were admitted in ward for elective clean surgery, same method
of skin preparation was under taken with povidone iodine and spirit.
Control were patients without surgical site infection while cases
were patients with surgical site infection. All patients received
three doses of prophylactic antibiotic first generation cephalosporin
500 mg i/v 8hourly preoperatively. SPSS version 10 was used to analyze
the data.
Results: The ages of the patients were between
18-55 years with increased risk of surgical site infection with
increasing age. Out of 50 patients with surgical site infection,
28 (56%) were diabetic and 22 (44%) were non-diabetic. It was seen
that 24 patients (16%) had surgery of duration 46-60 minutes and
12 of them (50%) had surgical site infection as compared to 36%
in surgery of less than 30 min. Odd ratio of infection for diabetes,
duration of surgery, age and gender were 10.3, 6.5, 3.1 and 1.3
respectively. Significant association was found between type, duration
of surgery and ASA score.
Conclusion: Adjusted analysis revealed a significant
relation between age, ASA class, diabetes mellitus, uncontrolled
postoperative blood glucose level, duration of surgery and surgical
site infection. Mastectomy was significantly associated with surgical
site infections along with longer duration and ASA class III
Key words: Surgical site infection, clean surgery,
uncontrolled blood glucose, duration.
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